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Nikon Debuts New Stereomicroscopes for Bioscience Applications

Nikon Instruments, Inc. today announced the introduction of two all new stereomicroscopes, its Nikon SMZ25 and SMZ18 systems. Ideal for all bioscience applications, these new microscopes meet the increasing need of scientists for imaging systems capable of spanning spatial scales from single cells to whole organisms.

New Features for World-Class Performance

The SMZ25 is fully-motorized. It utilizes the Nikon Perfect Zoom System, resulting in the world's first large zoom ratio of 25:1 for superior resolution and exceptional fluorescence transmission capability. The SMZ18 offers the same features, but is manual.

Both microscopes have the Auto Link Zoom feature, which automatically adjusts to maintain the same field of view when switching objective lenses, supporting seamless viewing at different scales. Both systems put ergonomic design front and center, enabling these features to be housed in a more compact zoom body.

The new systems are also the first stereomicroscopes to use a fly-eye lens on an epi-fluorescence attachment. This ensures bright and uniform illumination even at low magnifications, resulting in uncompromised uniformity in brightness across a large field of view.

Optical Design Improvements

Both the SMZ25 and SMZ18 also feature breakthroughs in optical design, resulting in significantly improved signal to noise ratio and crystal-clear fluorescent images.

Traditionally, researchers must switch to a higher magnification microscope to view microscopic details after using a stereomicroscope to view, or manipulate macroscopic structures. The SMZ25 and SMZ18 eliminate this need by providing both macroscopic and microscopic imaging capabilities. This, combined with Nikon's newly developed objective lens, the SHR Plan Apo series, offers a superior resolution never before seen on a stereomicroscope. The SHR Plan Apo 2x Objective, enables visualization of structures as small as a few microns, once considered to be impossible on a stereomicroscope. Apochromatic correction is maintained in both the objective lens and the optical zoom system, virtually eliminating color aberrations.

Even at low magnification, the SMZ25 series can captures an entire 35mm dish with equal brightness over the whole field of view, simultaneously delivering microscopic details. This feature is ideal for activities like live screening of developmental biology models such as C. elegans, drosophila, zebrafish or mice to identify and select mutants. Brilliant images can be captured even with low excitation light levels, minimizing photo-bleaching and photo-toxicity which is harmful to live cells and organisms.

Increased Usability, Easy Integration with Software

The SMZ25 remote control provides easy access to zoom and focus controls. Nikon's cross-platform NIS-Elements imaging and analysis software can be used to capture multi-channel time-lapse images, z-stacks and EDF images easily from a PC.

A slimmer diascopic illumination base helps increase the efficiency and ergonomics of sample manipulation. The new base also features a built-in Oblique Coherent Contrast illuminator that produces high-contrast images of transparent samples such as ITO film and zebrafish.

A wide range of accessories and illuminators accommodate a wide variety of observation methods.

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