Early results from the NeuroSIPE programme 'Beyond Pain'
project, in research funded by the Dutch Technology Foundation STW,
demonstrate how a FLIR SC5600 thermal imaging camera has been
used as an effective, non-invasive tool for monitoring of pain
processing in the central nervous system of patients suffering from
small fiber neuropathy.
neuropathy (SFN) is a sensory neuropathy that affects small fibers and
their functions. Currently there is not a gold standard for the
diagnosis of SFN. While skin biopsy provides an assessment of
intra-epidermal nerve fiber density, the technique is invasive,
labour-intensive and has limited accuracy. The goal of the 'Beyond Pain'
project is to develop a technique that enables quantitative and
non-invasive diagnosis of SFN.
SFN is known to
affect the local vasomotor response of skin. Using a method developed by
'Beyond Pain' project researchers a subjects skin is locally heated up
to a maximum of 42 C with an infrared lamp. The thermal response of the
skin is evaluated based on two signals: local skin blood flow, measured
with laser Doppler flowmetry and local skin temperature, measured with a
thermography camera (FLIR SC5600). The first results on healthy
volunteers demonstrate that the regulation of skin temperature can be
assessed with the new technique.
thermal imaging cameras are used for capturing and recording thermal
distribution and variations in real-time, allowing researchers to see
and accurately measure heat patterns, dissipation, leakage, and other
temperature factors in equipment, products and processes. These cameras
can distinguish temperature changes as subtle as 0.02°C. They feature
state-of-the-art detector technology and advanced mathematical
algorithms for high performance and precise measurements from -80°C to
+3000°C. The SC-Series R&D camera range combine extremely high
imaging performance and precise temperature measurements, with powerful
tools and software for analysing and reporting.